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Lizzie is a lizard monster and is usually depicted as the second of three main protagonists, the other two being George and Ralph.

She made her first debut in Rampage (1986), then reappeared in Rampage: World Tour, Rampage 2: Universal Tour, Rampage Through Time, Rampage: Puzzle Attack, and the most recent game in the series, Rampage: Total Destruction. She has made a continuous appearance ever since.

Origin

Lizzie was a lizard that was a pet of a young girl named Sally. When Sally accidentally dropped Lizzie into a nuclear sewer, she mutated into a giant monster.