After Spider-Man rid himself of the alien Symbiote that infected his life, it found and attached itself to Eddie Brock, a frustrated reporter who had a grudge against Spider-Man for, what he claims, making him lose his job. They became Venom, and as both hated Spider-Man, sought to destroy every aspect of his life. Venom had gained all the powers and knowledge of Spidey, only enhanced, however he seems to be absent of his spider sense.
- Venom has blue highlights in the mainstream comics and some versions and in the year 2000 Spider-Man game Venom is Dark Blue.
- In Ultimate Marvel and the Ultimate Spider-Man video game Venom is Dark Purple.